TLR7/TLR8 Activation Restores Defective Cytokine Secretion by Myeloid Dendritic Cells but Not by Plasmacytoid Dendritic Cells in HIV-Infected Pregnant Women and Newborns.

TLR7/TLR8 Activation Restores Defective Cytokine Secretion by Myeloid Dendritic Cells but Not by Plasmacytoid Dendritic Cells in HIV-Infected Pregnant Women and Newborns.

Mother-to-child transmission (MTCT) of HIV-1 has been significantly reduced with the use of antiretroviral therapies, resulting in an increased number of HIV-exposed uninfected infants. The consequences of HIV infection on the innate immune system of both mother-newborn are not well understood. In t...

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Bibliographic Details
Main Authors: Elaine Cristina Cardoso, Nátalli Zanete Pereira, Gabrielle Eimi Mitsunari, Luanda Mara da Silva Oliveira, Rosa Maria S A Ruocco, Rossana Pulcineli Vieira Francisco, Marcelo Zugaib, Alberto José da Silva Duarte, Maria Notomi Sato
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3694931?pdf=render

Internet

http://europepmc.org/articles/PMC3694931?pdf=render

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