Role and Cytotoxicity of Amylin and Protection of Pancreatic Islet β-Cells from Amylin Cytotoxicity

Amylin, (or islet amyloid polypeptide; IAPP), a 37-amino acid peptide hormone, is released in response to nutrients, including glucose, lipids or amino acids. Amylin is co-stored and co-secreted with insulin by pancreatic islet β-cells. Amylin inhibits food intake, delays gastric emptying,...

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Bibliographic Details
Main Authors: Yoshimitsu Kiriyama, Hiromi Nochi
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Cells
Subjects:
Online Access:http://www.mdpi.com/2073-4409/7/8/95