Comprehensive genetic screening of early-onset dementia patients in an Austrian cohort-suggesting new disease-contributing genes

Comprehensive genetic screening of early-onset dementia patients in an Austrian cohort-suggesting new disease-contributing genes

Abstract Early-onset dementia (EOD), with symptom onset before age 65, has a strong genetic burden. Due to genetic and clinical overlaps between different types of dementia, whole-exome sequencing (WES) has emerged as an appropriate screening method for diagnostic testing and novel gene-finding appr...

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Bibliographic Details
Main Authors: Sara Silvaieh, Theresa König, Raphael Wurm, Tandis Parvizi, Evelyn Berger-Sieczkowski, Stella Goeschl, Christoph Hotzy, Matias Wagner, Riccardo Berutti, Esther Sammler, Elisabeth Stögmann, Alexander Zimprich
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Human Genomics
Subjects:
Early-onset dementia
Whole-exome sequencing
Genetic variants
Online Access:https://doi.org/10.1186/s40246-023-00499-z

Internet

https://doi.org/10.1186/s40246-023-00499-z

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