Movement of accessible plasma membrane cholesterol by the GRAMD1 lipid transfer protein complex

Movement of accessible plasma membrane cholesterol by the GRAMD1 lipid transfer protein complex

Cholesterol is a major structural component of the plasma membrane (PM). The majority of PM cholesterol forms complexes with other PM lipids, making it inaccessible for intracellular transport. Transition of PM cholesterol between accessible and inaccessible pools maintains cellular homeostasis, but...

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Bibliographic Details
Main Authors: Tomoki Naito, Bilge Ercan, Logesvaran Krshnan, Alexander Triebl, Dylan Hong Zheng Koh, Fan-Yan Wei, Kazuhito Tomizawa, Federico Tesio Torta, Markus R Wenk, Yasunori Saheki
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-11-01
Series:eLife
Subjects:
cholesterol
GRAM domain
membrane contact sites
StART-like domain
non-vesicular lipid transport
plasma membrane
Online Access:https://elifesciences.org/articles/51401

Internet

https://elifesciences.org/articles/51401

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