Performance and Value of IFN-Lambda3 and IFN-Lambda4 Genotyping in Patients with Chronic Hepatitis C (CHC) Genotype 2/3 in a Real World Setting.

Performance and Value of IFN-Lambda3 and IFN-Lambda4 Genotyping in Patients with Chronic Hepatitis C (CHC) Genotype 2/3 in a Real World Setting.

<h4>Background</h4>SNPs near the interferon lambda (IFNL) 3 gene are predictors for sustained virological response (SVR) in patients with chronic hepatitis C genotype (GT) 1. In addition, a dinucleotide frame shift in ss469415590 was described, which generates IFNL4. In this study, we co...

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Main Authors: Steffen B Wiegand, Benjamin Heidrich, Simone Susser, Magdalena Rogalska-Taranta, Jörg Petersen, Klaus H W Böker, Natalia Grigorian, Ralph Link, Uwe Naumann, Christine John, Stefan Lueth, Peter Malfertheiner, Michael P Manns, Heiner Wedemeyer, Christoph Sarrazin, Markus Cornberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0145622&type=printable

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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0145622&type=printable

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