Synthesis of novel amodiaquine analogs and evaluation of their in vitro and in vivo antimalarial activities
Background & objectives: Due to the rapid increase of drug resistance in Plasmodium parasites, there is a pressing need of developing new antiplasmodial drugs. In this study, new amodiaquine (AQ) analogs were synthesized, followed by an evaluation of their antiplasmodial activity. Methods: A new...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2019-01-01
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Series: | Journal of Vector Borne Diseases |
Subjects: | |
Online Access: | http://www.jvbd.org/article.asp?issn=0972-9062;year=2019;volume=56;issue=3;spage=221;epage=230;aulast=Tahghighi |