The Lung Alveolar Cell (LAC) miRNome and Gene Expression Profile of the SP-A-KO Mice After Infection With and Without Rescue With Human Surfactant Protein-A2 (1A0)

The Lung Alveolar Cell (LAC) miRNome and Gene Expression Profile of the SP-A-KO Mice After Infection With and Without Rescue With Human Surfactant Protein-A2 (1A0)

Human surfactant protein (SP)-A1 and SP-A2 exhibit differential qualitative and quantitative effects on the alveolar macrophage (AM), including a differential impact on the AM miRNome. Moreover, SP-A rescue (treatment) of SP-A-knockout (KO) infected mice impoves survival. Here, we studied for the fi...

Full description

Bibliographic Details
Main Authors: Nithyananda Thorenoor, Joanna Floros
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
surfactant protein A2
lung alveolar cells
alveolar macrophages
Klebsiella pneumoniae
miRNome
gene expression
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.854434/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.854434/full

Similar Items