PSTPIP2 inhibits cisplatin-induced acute kidney injury by suppressing apoptosis of renal tubular epithelial cells

Abstract Cisplatin (CP) is an effective chemotherapeutic agent widely used in the treatment of various solid tumours. However, CP nephrotoxicity is an important limitation for CP use; currently, there is no method to ameliorate cisplatin-induced acute kidney injury (AKI). Recently, we identified a s...

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Bibliographic Details
Main Authors: Hong Zhu, Wenjuan Jiang, Huizi Zhao, Changsheng He, Xiaohan Tang, Songbing Xu, Chuanting Xu, Rui Feng, Jun Li, Taotao Ma, Cheng Huang
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-020-03267-2