Catabolic Ornithine Carbamoyltransferase Activity Facilitates Growth of Staphylococcus aureus in Defined Medium Lacking Glucose and Arginine

Catabolic Ornithine Carbamoyltransferase Activity Facilitates Growth of Staphylococcus aureus in Defined Medium Lacking Glucose and Arginine

ABSTRACT Previous studies have found that arginine biosynthesis in Staphylococcus aureus is repressed via carbon catabolite repression (CcpA), and proline is used as a precursor. Unexpectedly, however, robust growth of S. aureus is not observed in complete defined medium lacking both glucose and arg...

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Bibliographic Details
Main Authors: Itidal Reslane, Cortney R. Halsey, Amanda Stastny, Barbara J. Cabrera, Jongsam Ahn, Dhananjay Shinde, Madeline R. Galac, Margaret F. Sladek, Fareha Razvi, McKenzie K. Lehman, Kenneth W. Bayles, Vinai C. Thomas, Luke D. Handke, Paul D. Fey
Format: Article
Language:English
Published: American Society for Microbiology 2022-06-01
Series:mBio
Subjects:
arginine biosynthesis
Staphylococcus aureus
auxotrophy
transcriptional regulation
Online Access:https://journals.asm.org/doi/10.1128/mbio.00395-22

Internet

https://journals.asm.org/doi/10.1128/mbio.00395-22

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