An agonistic anti-Tie2 antibody suppresses the normal-to-tumor vascular transition in the glioblastoma invasion zone

An agonistic anti-Tie2 antibody suppresses the normal-to-tumor vascular transition in the glioblastoma invasion zone

Brain tumours: antibody blocks blood vessel abnormality An antibody targeting key signalling pathways could prevent brain tumor vessels from being abnormal, thereby improving drug delivery into tumor tissues. Glioblastoma multiforme is considered one of the most deadly cancers and it invades brain t...

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Bibliographic Details
Main Authors: Eunhyeong Lee, Eun-Ah Lee, Eunji Kong, Haemin Chon, Melissa Llaiqui-Condori, Cheon Ho Park, Beom Yong Park, Nu Ri Kang, Jin-San Yoo, Hyun-Soo Lee, Hyung-Seok Kim, Sung-Hong Park, Seung-Won Choi, Dietmar Vestweber, Jeong Ho Lee, Pilhan Kim, Weon Sup Lee, Injune Kim
Format: Article
Language:English
Published: Nature Publishing Group 2023-02-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-023-00939-9

Internet

https://doi.org/10.1038/s12276-023-00939-9

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