Staphylococcus aureus stimulates neutrophil itaconate production that suppresses the oxidative burst

Summary: Neutrophils are critical in the host defense against Staphylococcus aureus, a major human pathogen. However, even in the setting of a robust neutrophil response, S. aureus can evade immune clearance. Here, we demonstrate that S. aureus impairs neutrophil function by triggering the productio...

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Bibliographic Details
Main Authors: Kira L. Tomlinson, Sebastián A. Riquelme, Swikrity Upadhyay Baskota, Marija Drikic, Ian R. Monk, Timothy P. Stinear, Ian A. Lewis, Alice S. Prince
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S221112472300075X