Transcript and protein signatures derived from shared molecular interactions across cancers are associated with mortality

Transcript and protein signatures derived from shared molecular interactions across cancers are associated with mortality

Abstract Background Characterization of shared cancer mechanisms have been proposed to improve therapy strategies and prognosis. Here, we aimed to identify shared cell–cell interactions (CCIs) within the tumor microenvironment across multiple solid cancers and assess their association with cancer mo...

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Bibliographic Details
Main Authors: Yelin Zhao, Xinxiu Li, Joseph Loscalzo, Martin Smelik, Oleg Sysoev, Yunzhang Wang, A. K. M. Firoj Mahmud, Dina Mansour Aly, Mikael Benson
Format: Article
Language:English
Published: BMC 2024-05-01
Series:Journal of Translational Medicine
Subjects:
Cell–cell interactions
Cancer-associated fibroblast
Single-cell RNA sequencing
Prioritization
Pan-cancer
Mortality
Online Access:https://doi.org/10.1186/s12967-024-05268-7

Internet

https://doi.org/10.1186/s12967-024-05268-7

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