Clinical pharmacology and dosing regimen optimization of neonatal opioid withdrawal syndrome treatments

Abstract In this paper, we review the management of neonatal opioid withdrawal syndrome (NOWS) and clinical pharmacology of primary treatment agents in NOWS, including morphine, methadone, buprenorphine, clonidine, and phenobarbital. Pharmacologic treatment strategies in NOWS have been mostly empiri...

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Bibliographic Details
Main Authors: Fei Tang, Chee M. Ng, Henrietta S. Bada, Markos Leggas
Format: Article
Language:English
Published: Wiley 2021-07-01
Series:Clinical and Translational Science
Online Access:https://doi.org/10.1111/cts.12994