Polymorphism rs7079 in miR-31/-584 Binding Site in Angiotensinogen Gene Associates with Earlier Onset of Coronary Artery Disease in Central European Population

Polymorphism rs7079 in miR-31/-584 Binding Site in Angiotensinogen Gene Associates with Earlier Onset of Coronary Artery Disease in Central European Population

Angiotensinogen (AGT) represents a key component of the renin–angiotensin–aldosterone system (RAAS). Polymorphisms in the 3′ untranslated region (3′UTR) of the AGT gene may alter miRNA binding and cause disbalance in the RAAS. Within this study, we evaluated the possible association of AGT +11525C/A...

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Bibliographic Details
Main Authors: Jan Novák, Soňa Maceková, Renata Héžová, Jan Máchal, Filip Zlámal, Ota Hlinomaz, Michal Rezek, Miroslav Souček, Anna Vašků, Ondřej Slabý, Julie Bienertová-Vašků
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Genes
Subjects:
rs7079
angiotensinogen
restenosis
age
coronary artery disease
Online Access:https://www.mdpi.com/2073-4425/13/11/1981

Internet

https://www.mdpi.com/2073-4425/13/11/1981

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