Effect of Administration Route on the Pharmacokinetics of Cobalamin in Elderly Patients: A Randomized Controlled Trial

Effect of Administration Route on the Pharmacokinetics of Cobalamin in Elderly Patients: A Randomized Controlled Trial

Background: The gold standard for cobalamin deficiency treatment is administration of cobalamin by intramuscular injection. The injection is painful and inconvenient, particularly for elderly persons. Cobalamin might also be administered intranasally. Previous studies do not provide insight into the...

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Main Authors: Monique P.H. Tillemans, PharmD, Eline M.V.J. Donders, MD, Sjoerd L. Verweij, PharmD, Ruud T.M. Van der Hoeven, PharmD, Kees J. Kalisvaart, MD, PhD
Format: Article
Language:English
Published: Elsevier 2014-12-01
Series:Current Therapeutic Research
Subjects:
cobalamin
elderly
intramuscular
intranasal
pharmacokinetics
Online Access:http://www.sciencedirect.com/science/article/pii/S0011393X14000022

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http://www.sciencedirect.com/science/article/pii/S0011393X14000022

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