Teasing apart translational and transcriptional components of stochastic variations in eukaryotic gene expression.

The intrinsic stochasticity of gene expression leads to cell-to-cell variations, noise, in protein abundance. Several processes, including transcription, translation, and degradation of mRNA and proteins, can contribute to these variations. Recent single cell analyses of gene expression in yeast hav...

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Bibliographic Details
Main Authors: Raheleh Salari, Damian Wojtowicz, Jie Zheng, David Levens, Yitzhak Pilpel, Teresa M Przytycka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3431295?pdf=render