Loss of primary cilia promotes mitochondria-dependent apoptosis in thyroid cancer

Abstract The primary cilium is well-preserved in human differentiated thyroid cancers such as papillary and follicular carcinoma. Specific thyroid cancers such as Hürthle cell carcinoma, oncocytic variant of papillary thyroid carcinoma (PTC), and PTC with Hashimoto’s thyroiditis show reduced biogene...

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Bibliographic Details
Main Authors: Junguee Lee, Ki Cheol Park, Hae Joung Sul, Hyun Jung Hong, Kun-Ho Kim, Jukka Kero, Minho Shong
Format: Article
Language:English
Published: Nature Portfolio 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-83418-3