Interaction of isoquinoline alkaloids with pyrimidine motif triplex DNA by mass spectrometry and spectroscopies reveals diverse mechanisms

Interaction of isoquinoline alkaloids with pyrimidine motif triplex DNA by mass spectrometry and spectroscopies reveals diverse mechanisms

Isoquinoline alkaloids represent an important class of molecules due to their broad range of pharmacology and clinical utility. Prospective development and use of these alkaloids as effective anticancer agents have elicited great interest. In this study, in order to reveal structure-activity relatio...

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Bibliographic Details
Main Authors: Zhaoyang Xie, Sunuo Zhang, Yi Wu, Jinling Liang, Wenbin Yao, Ruoning Qu, Xiaole Tong, Guang Zhang, Hongmei Yang
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Heliyon
Subjects:
Triplex DNA
Isoquinoline alkaloids
Interaction
Mass spectrometry
Spectroscopy
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023021618

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http://www.sciencedirect.com/science/article/pii/S2405844023021618

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