Proteome-wide analysis of cysteine oxidation reveals metabolic sensitivity to redox stress
Reactive oxygen species can modify cysteine residues on proteins to control cellular signalling. Here, the authors develop a proteomics approach to assess cysteine oxidation dynamics in cells and primary tissues, monitoring oxidative stress-induced metabolic adaptations and oxidation states of biofl...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2018-04-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-018-04003-3 |