Proteome-wide analysis of cysteine oxidation reveals metabolic sensitivity to redox stress

Reactive oxygen species can modify cysteine residues on proteins to control cellular signalling. Here, the authors develop a proteomics approach to assess cysteine oxidation dynamics in cells and primary tissues, monitoring oxidative stress-induced metabolic adaptations and oxidation states of biofl...

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Bibliographic Details
Main Authors: Jiska van der Reest, Sergio Lilla, Liang Zheng, Sara Zanivan, Eyal Gottlieb
Format: Article
Language:English
Published: Nature Portfolio 2018-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-04003-3