Associations of plasma neurofilament light chain with cognition and neuroimaging measures in community-dwelling early old age men

Associations of plasma neurofilament light chain with cognition and neuroimaging measures in community-dwelling early old age men

Abstract Background Plasma neurofilament light chain (NfL) is a promising biomarker of neurodegeneration with potential clinical utility in monitoring the progression of neurodegenerative diseases. However, the cross-sectional associations of plasma NfL with measures of cognition and brain have been...

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Bibliographic Details
Main Authors: Rongxiang Tang, Erik Buchholz, Anders M. Dale, Robert A. Rissman, Christine Fennema-Notestine, Nathan A. Gillespie, Donald J Hagler, Michael J. Lyons, Michael C. Neale, Matthew S. Panizzon, Olivia K. Puckett, Chandra A. Reynolds, Carol E. Franz, William S. Kremen, Jeremy A. Elman
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Alzheimer’s Research & Therapy
Subjects:
Neurofilament light chain
White matter hyperintensity
Processing speed
Neurodegeneration
Blood-based biomarkers
Online Access:https://doi.org/10.1186/s13195-024-01464-1

Internet

https://doi.org/10.1186/s13195-024-01464-1

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