Contribution of macrophages to neural survival and intracochlear tissue remodeling responses following cochlear implantation

Contribution of macrophages to neural survival and intracochlear tissue remodeling responses following cochlear implantation

Abstract Background Cochlear implants (CIs) restore hearing to deafened patients. The foreign body response (FBR) following cochlear implantation (post-CI) comprises an infiltration of macrophages, other immune and non-immune cells, and fibrosis into the scala tympani, a space that is normally devoi...

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Bibliographic Details
Main Authors: Muhammad Taifur Rahman, Brian J. Mostaert, Bryce Hunger, Utsow Saha, Alexander D. Claussen, Ibrahim Razu, Farjana Nasrin, Nashwaan Ali Khan, Peter Eckard, Sarah Coleman, Jacob Oleson, Jonathon R. Kirk, Keiko Hirose, Marlan R. Hansen
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Neuroinflammation
Subjects:
Cochlear implant
Foreign body response
Fibrosis
Biomaterials
Inflammation
Online Access:https://doi.org/10.1186/s12974-023-02955-y

Internet

https://doi.org/10.1186/s12974-023-02955-y

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