A Simple, Cost-Effective, and Robust Method for rRNA Depletion in RNA-Sequencing Studies

ABSTRACT The profiling of gene expression by RNA sequencing (RNA-seq) has enabled powerful studies of global transcriptional patterns in all organisms, including bacteria. Because the vast majority of RNA in bacteria is rRNA, it is standard practice to deplete the rRNA from a total RNA sample such t...

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Bibliographic Details
Main Authors: Peter H. Culviner, Chantal K. Guegler, Michael T. Laub
Format: Article
Language:English
Published: American Society for Microbiology 2020-04-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mBio.00010-20