Evolutionary action of mutations reveals antimicrobial resistance genes in Escherichia coli

Evolutionary action of mutations reveals antimicrobial resistance genes in Escherichia coli

The emergence of antibiotic resistance, even against last-line antibiotics such as colistin, is a serious public health threat. To guide treatment and drug development strategies, Marciano et al. apply evolutionary action (EA) analysis to identify driver mutations in a noisy mutational background in...

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Bibliographic Details
Main Authors: David C. Marciano, Chen Wang, Teng-Kuei Hsu, Thomas Bourquard, Benu Atri, Ralf B. Nehring, Nicholas S. Abel, Elizabeth A. Bowling, Taylor J. Chen, Pamela D. Lurie, Panagiotis Katsonis, Susan M. Rosenberg, Christophe Herman, Olivier Lichtarge
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-30889-1

Internet

https://doi.org/10.1038/s41467-022-30889-1

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