Evolutionary action of mutations reveals antimicrobial resistance genes in Escherichia coli
The emergence of antibiotic resistance, even against last-line antibiotics such as colistin, is a serious public health threat. To guide treatment and drug development strategies, Marciano et al. apply evolutionary action (EA) analysis to identify driver mutations in a noisy mutational background in...
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Bibliographic Details
| Main Authors: |
David C. Marciano,
Chen Wang,
Teng-Kuei Hsu,
Thomas Bourquard,
Benu Atri,
Ralf B. Nehring,
Nicholas S. Abel,
Elizabeth A. Bowling,
Taylor J. Chen,
Pamela D. Lurie,
Panagiotis Katsonis,
Susan M. Rosenberg,
Christophe Herman,
Olivier Lichtarge |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2022-06-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-022-30889-1
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