Pharmacogenomic profile of actionable molecular variants related to drugs commonly used in anesthesia: WES analysis reveals new mutations

Pharmacogenomic profile of actionable molecular variants related to drugs commonly used in anesthesia: WES analysis reveals new mutations

Background: Genetic interindividual variability is associated with adverse drug reactions (ADRs) and affects the response to common drugs used in anesthesia. Despite their importance, these variants remain largely underexplored in Latin-American countries. This study describes rare and common varian...

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Bibliographic Details
Main Authors: Juan Fernando Parada-Márquez, Nicolás David Maldonado-Rodriguez, Paula Triana-Fonseca, Nora Constanza Contreras-Bravo, Carlos Alberto Calderón-Ospina, Carlos M. Restrepo, Adrien Morel, Oscar Javier Ortega-Recalde, Daniel Felipe Silgado-Guzmán, Mariana Angulo-Aguado, Dora Janeth Fonseca-Mendoza
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Pharmacology
Subjects:
next-generation sequencing
pharmacogenomics
allelic frequency
molecular variants
anesthesia drugs
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1047854/full

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https://www.frontiersin.org/articles/10.3389/fphar.2023.1047854/full

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