Therapeutic potential of polyphenols against aging- induced idiopathic pulmonary fibrosis (IPF) via Bioinformatics analysis

Background: Hyperactivation of Akt/mTORC1 is known to be the mechanistic driver for idiopathic pulmonary fibrosis (IPF) induction in elderly population. Stimulation of Aryl hydrocarbon receptor (AhR) under physiological stress is largely associated with Akt/mTORC1 inhibition upon aging. This in turn...

Full description

Bibliographic Details
Main Authors: Ankit Tripathi, Deepika Tripathi, Manish Shukla, Meenakshi Sharma
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Phytomedicine Plus
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667031323000969