Are Proteinopathy and Oxidative Stress Two Sides of the Same Coin?
Parkinson’s disease, like other neurodegenerative diseases, exhibits two common features: Proteinopathy and oxidative stress, leading to protein aggregation and mitochondrial damage respectively. Because both protein aggregates and dysfunctional mitochondria are eliminated by autophagy, we...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-01-01
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Series: | Cells |
Subjects: | |
Online Access: | http://www.mdpi.com/2073-4409/8/1/59 |