Are Proteinopathy and Oxidative Stress Two Sides of the Same Coin?

Parkinson’s disease, like other neurodegenerative diseases, exhibits two common features: Proteinopathy and oxidative stress, leading to protein aggregation and mitochondrial damage respectively. Because both protein aggregates and dysfunctional mitochondria are eliminated by autophagy, we...

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Bibliographic Details
Main Authors: Nihar J. Mehta, Praneet Kaur Marwah, David Njus
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Cells
Subjects:
Online Access:http://www.mdpi.com/2073-4409/8/1/59