Novel mutations of RPGR in Chinese families with X-linked retinitis pigmentosa

Novel mutations of RPGR in Chinese families with X-linked retinitis pigmentosa

Abstract Background RP (retinitis pigmentosa) is a group of hereditary retinal degenerative diseases. XLRP is a relatively severe subtype of RP. Thus, it is necessary to identify genes and mutations in patients who present with X-linked retinitis pigmentosa. Methods Genomic DNA was extracted from pe...

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Bibliographic Details
Main Authors: Zhimeng Zhang, Hehua Dai, Lei Wang, Tianchang Tao, Jing Xu, Xiaowei Sun, Liping Yang, Genlin Li
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Ophthalmology
Subjects:
RPGR
X-linked retinitis pigmentosa
ORF15
Nonsense mutation
Pathological myopia
Online Access:http://link.springer.com/article/10.1186/s12886-019-1250-7

Internet

http://link.springer.com/article/10.1186/s12886-019-1250-7

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