Predicting variant deleteriousness in non-human species: applying the CADD approach in mouse

Predicting variant deleteriousness in non-human species: applying the CADD approach in mouse

Abstract Background Predicting the deleteriousness of observed genomic variants has taken a step forward with the introduction of the Combined Annotation Dependent Depletion (CADD) approach, which trains a classifier on the wealth of available human genomic information. This raises the question whet...

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Bibliographic Details
Main Authors: Christian Groß, Dick de Ridder, Marcel Reinders
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Bioinformatics
Subjects:
Genomics
Genome annotation
Variant annotation
Sequence annotation
Mouse genetics
Online Access:http://link.springer.com/article/10.1186/s12859-018-2337-5

Internet

http://link.springer.com/article/10.1186/s12859-018-2337-5

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