Molecular and Phenotypic Changes in FLExDUX4 Mice

Facioscapulohumeral muscular dystrophy (FSHD) is caused by the aberrant expression of the double homeobox 4 (<i>DUX4</i>) gene. The <i>FLExDUX4</i> mouse model carries an inverted human <i>DUX4</i> transgene which has leaky <i>DUX4</i> transgene expres...

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Bibliographic Details
Main Authors: Kelly Murphy, Aiping Zhang, Adam J. Bittel, Yi-Wen Chen
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Journal of Personalized Medicine
Subjects:
Online Access:https://www.mdpi.com/2075-4426/13/7/1040