Dual-Activated Nano-Prodrug for Chemo-Photodynamic Combination Therapy of Breast Cancer

Dual-Activated Nano-Prodrug for Chemo-Photodynamic Combination Therapy of Breast Cancer

Herein, we developed a dual-activated prodrug, BTC, that contains three functional components: a glutathione (GSH)-responsive BODIPY-based photosensitizer with a photoinduced electron transfer (PET) effect between BODIPY and the 2,4-dinitrobenzenesulfonate (DNBS) group, and an ROS-responsive thioket...

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Bibliographic Details
Main Authors: Ziyao Lu, Gan Xu, Xiaozhen Yang, Shijia Liu, Yang Sun, Li Chen, Qinying Liu, Jianyong Liu
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
nano-prodrug
photodynamic therapy
reactive oxygen species
activation
combination therapy
Online Access:https://www.mdpi.com/1422-0067/23/24/15656

Internet

https://www.mdpi.com/1422-0067/23/24/15656

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