Recent Overview of the Use of iPSCs Huntington’s Disease Modeling and Therapy

Huntington’s disease (HD) is an inherited, autosomal dominant, degenerative disease characterized by involuntary movements, cognitive decline, and behavioral impairment ending in death. HD is caused by an expansion in the number of CAG repeats in the huntingtin gene on chromosome 4. To dat...

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Bibliographic Details
Main Authors: Maria Csobonyeiova, Stefan Polak, Lubos Danisovic
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/6/2239