An antifouling membrane-fusogenic liposome for effective intracellular delivery in vivo
Abstract The membrane-fusion-based internalization without lysosomal entrapment is advantageous for intracellular delivery over endocytosis. However, protein corona formed on the membrane-fusogenic liposome surface converts its membrane-fusion performance to lysosome-dependent endocytosis, causing p...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-05-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-024-46533-z |