Study of the biological properties of attenuated variants of the virulent A/WSN/33 strain of influenza virus, obtained by the site-specific mutagenesis of PB2-gene

Study of the biological properties of attenuated variants of the virulent A/WSN/33 strain of influenza virus, obtained by the site-specific mutagenesis of PB2-gene

Aim. Study of biological properties of attenuated  variants of the virulent A/WSN/33 strain of influenza virus, obtained by the site-specific mutagenesis of PB2-gene. Materials and methods. Site-specific mutants of A/WSN/33 of influenza virus, having in PB2-gene ts-mutations from genome of cold-adap...

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Bibliographic Details
Main Authors: V. Yu. Kost, A. A. Rtischev, R. R. Mintaev, I. I. Akopova, K. V. Lisovskaya, S. G. Markushin
Format: Article
Language:Russian
Published: Central Research Institute for Epidemiology 2019-08-01
Series:Журнал микробиологии, эпидемиологии и иммунобиологии
Subjects:
influenza virus
site-specific mutagenesis
ts-phenotype
att-phenotype
protective efficacy
homologous and heterologous control infections
attenuation
Online Access:https://microbiol.elpub.ru/jour/article/view/393

Internet

https://microbiol.elpub.ru/jour/article/view/393

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