First-in-human use of 11C-CPPC with positron emission tomography for imaging the macrophage colony-stimulating factor 1 receptor

First-in-human use of 11C-CPPC with positron emission tomography for imaging the macrophage colony-stimulating factor 1 receptor

Abstract Purpose Study of the contribution of microglia to onset and course of several neuropsychiatric conditions is challenged by the fact that these resident immune cells often take on different phenotypes and functions outside the living brain. Imaging microglia with radiotracers developed for u...

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Bibliographic Details
Main Authors: Jennifer M. Coughlin, Yong Du, Wojciech G. Lesniak, Courtney K. Harrington, Mary Katherine Brosnan, Riley O’Toole, Adeline Zandi, Shannon Eileen Sweeney, Rehab Abdallah, Yunkou Wu, Daniel P. Holt, Andrew W. Hall, Robert F. Dannals, Lilja Solnes, Andrew G. Horti, Martin G. Pomper
Format: Article
Language:English
Published: SpringerOpen 2022-09-01
Series:EJNMMI Research
Subjects:
Human PET neuroimaging
Microglia
CSF1R
Neuroinflammation
PET
Online Access:https://doi.org/10.1186/s13550-022-00929-4

Internet

https://doi.org/10.1186/s13550-022-00929-4

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