Robustness of DNA repair through collective rate control.

DNA repair and other chromatin-associated processes are carried out by enzymatic macromolecular complexes that assemble at specific sites on the chromatin fiber. How the rate of these molecular machineries is regulated by their constituent parts is poorly understood. Here we quantify nucleotide-exci...

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Bibliographic Details
Main Authors: Paul Verbruggen, Tim Heinemann, Erik Manders, Gesa von Bornstaedt, Roel van Driel, Thomas Höfer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24499930/pdf/?tool=EBI