Molecular mechanism of phospholipid transport at the bacterial outer membrane interface
Abstract The outer membrane (OM) of Gram-negative bacteria is an asymmetric lipid bilayer with outer leaflet lipopolysaccharides and inner leaflet phospholipids (PLs). This unique lipid asymmetry renders the OM impermeable to external insults, including antibiotics and bile salts. To maintain this b...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-12-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-023-44144-8 |