Mutations, inflammation and phenotype of myeloproliferative neoplasms

Mutations, inflammation and phenotype of myeloproliferative neoplasms

Knowledge on the myeloproliferative neoplasms (MPNs) – polycythemia vera (PV), essential thrombocythemia (ET), primary myelofibrosis (PMF) – has accumulated since the discovery of the JAK/STAT-activating mutations associated with MPNs: JAK2V617F, observed in PV, ET and PMF; and the MPL and CALR muta...

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Bibliographic Details
Main Author: Sylvie Hermouet
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Oncology
Subjects:
myeloproliferative neoplasms (MPN)
polycythemia vera
essential thrombocythemia inflammation
therapeutic targets
primary fibrosis (PMF)
mutations
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1196817/full

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https://www.frontiersin.org/articles/10.3389/fonc.2023.1196817/full

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