β-catenin ISGylation promotes lipid deposition and apoptosis in ethanol-stimulated liver injury models

β-catenin ISGylation promotes lipid deposition and apoptosis in ethanol-stimulated liver injury models

Background The restoration of the Wnt/β-catenin pathway to alleviate alcoholic fatty liver disease (AFLD) progression is under study as a new strategy for alcoholic liver disease (ALD) treatment. Recent studies have indicated that interferon-stimulated gene 15 (ISG15) can covalently bind to β-cateni...

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Bibliographic Details
Main Authors: Qi Ding, Guodong Zhang, Yang Wang, Lei Xu, Meifei Wu, Yiwen Zhou, Tao Xu, Xiaoming Meng, Cheng Huang, Lei Zhang
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Redox Report
Subjects:
Alcoholic fatty liver disease
ISG15
HERC5
β-catenin ISGylation
ROS
Wnt signaling pathway
Online Access:https://www.tandfonline.com/doi/10.1080/13510002.2022.2109360

Internet

https://www.tandfonline.com/doi/10.1080/13510002.2022.2109360

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