Different transport routes for high density lipoprotein and its associated free sterol in polarized hepatic cells
We analyzed the intracellular transport of HDL and its associated free sterol in polarized human hepatoma HepG2 cells. Using pulse-chase protocols, we demonstrated that HDL labeled with Alexa 488 at the apolipoprotein (Alexa 488-HDL) was internalized by a scavenger receptor class B type I (SR-BI)-de...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2004-03-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520318708 |