Anti-ceramide single-chain variable fragment mitigates radiation GI syndrome mortality independent of DNA repair

Anti-ceramide single-chain variable fragment mitigates radiation GI syndrome mortality independent of DNA repair

After 9/11, threat of nuclear attack on American urban centers prompted government agencies to develop medical radiation countermeasures to mitigate hematopoietic acute radiation syndrome (H-ARS) and higher-dose gastrointestinal acute radiation syndrome (GI-ARS) lethality. While repurposing leukemia...

Full description

Bibliographic Details
Main Authors: Jimmy A. Rotolo, Chii Shyang Fong, Sahra Bodo, Prashanth K.B. Nagesh, John Fuller, Thivashnee Sharma, Alessandra Piersigilli, Zhigang Zhang, Zvi Fuks, Vijay K. Singh, Richard Kolesnick
Format: Article
Language:English
Published: American Society for Clinical investigation 2021-04-01
Series:JCI Insight
Subjects:
Stem cells
Vascular biology
Online Access:https://doi.org/10.1172/jci.insight.145380

Internet

https://doi.org/10.1172/jci.insight.145380

Similar Items