Actin-like protein 6A/MYC/CDK2 axis confers high proliferative activity in triple-negative breast cancer

Actin-like protein 6A/MYC/CDK2 axis confers high proliferative activity in triple-negative breast cancer

Abstract Background Triple negative breast cancer (TNBC) is an aggressive subtype of breast cancer with high proliferative activity. TNBC tumors exhibit elevated MYC expression and altered expression of MYC regulatory genes, which are associated with tumor progression and poor prognosis; however, th...

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Bibliographic Details
Main Authors: Yunting Jian, Xinjian Huang, Lishan Fang, Meng Wang, Qinghua Liu, Hongyi Xu, Lingzhi Kong, Xiangfu Chen, Ying Ouyang, Xi Wang, Weidong Wei, Libing Song
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
TNBC
Proliferation
ACTL6A
MYC
CDK2 inhibitor
Online Access:https://doi.org/10.1186/s13046-021-01856-3

Internet

https://doi.org/10.1186/s13046-021-01856-3

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