Active search of adult patients with persistently low serum alkaline phosphatase levels for the diagnosis of hypophosphatasia

ABSTRACT Objectives: Alkaline phosphatase (ALP) is the main laboratory marker of hypophosphatasia (HPP), a rare disease unknown to most physicians. The prevalence of HPP has been widely discussed in the literature due to the diverse phenotypes of HPP. The purpose of this study was to search for pat...

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Bibliographic Details
Main Authors: Lucio Henrique Rocha Vieira, Kleison Cordeiro Peixoto, Caroline Leal Flósi, Maria Lucia Fleiuss de Farias, Miguel Madeira
Format: Article
Language:English
Published: Brazilian Society of Endocrinology and Metabolism 2021-04-01
Series:Archives of Endocrinology and Metabolism
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972021000300289&tlng=en