Recovery of function in a myogenic mouse model of spinal bulbar muscular atrophy

Recovery of function in a myogenic mouse model of spinal bulbar muscular atrophy

With this paper, we deliberately challenge the prevailing neurocentric theory of the etiology of spinal bulbar muscular atrophy (SBMA). We offer data supporting an alternative view that androgen receptor (AR) acts in skeletal muscles to cause the symptoms of SBMA. While SBMA has been linked to a CAG...

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Bibliographic Details
Main Authors: Jamie A. Johansen, Zhigang Yu, Kaiguo Mo, D. Ashley Monks, Andrew P. Lieberman, S. Marc Breedlove, Cynthia L. Jordan
Format: Article
Language:English
Published: Elsevier 2009-04-01
Series:Neurobiology of Disease
Subjects:
Polyglutamine
Kennedy's Disease
Androgens
Muscle
Transgenic
Motor neuron
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996108003215

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http://www.sciencedirect.com/science/article/pii/S0969996108003215

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