The Temperature-Dependent Effectiveness of Platinum-Based Drugs Mitomycin-C and 5-FU during Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Colorectal Cancer Cell Lines

The Temperature-Dependent Effectiveness of Platinum-Based Drugs Mitomycin-C and 5-FU during Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Colorectal Cancer Cell Lines

Cytoreductive surgery (CRS) followed by hyperthermic intraperitoneal chemotherapy (HIPEC) is a treatment with curative intent for peritoneal metastasis of colorectal cancer (CRC). Currently, there is no standardized HIPEC protocol: choice of drug, perfusate temperature, and duration of treatment var...

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Bibliographic Details
Main Authors: Roxan F.C.P.A. Helderman, Daan R. Löke, Jan Verhoeff, Hans M. Rodermond, Gregor G.W. van Bochove, Menno Boon, Sanne van Kesteren, Juan J. Garcia Vallejo, H. Petra Kok, Pieter J. Tanis, Nicolaas A.P. Franken, Johannes Crezee, Arlene L. Oei
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cells
Subjects:
hyperthermic intraperitoneal chemotherapy
HIPEC
colorectal cancer
platinum-based drugs
mitomycin-C
5-fluorouracil
Online Access:https://www.mdpi.com/2073-4409/9/8/1775

Internet

https://www.mdpi.com/2073-4409/9/8/1775

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