Transcriptional and Phenotypic Characterization of Novel Spx-Regulated Genes in Streptococcus mutans.

In oral biofilms, two of the major environmental challenges encountered by the dental pathogen Streptococcus mutans are acid and oxidative stresses. Previously, we showed that the S. mutans transcriptional regulators SpxA1 and SpxA2 (formerly SpxA and SpxB, respectively) are involved in stress survi...

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Bibliographic Details
Main Authors: Lívia C C Galvão, James H Miller, Jessica K Kajfasz, Kathy Scott-Anne, Irlan A Freires, Gilson C N Franco, Jacqueline Abranches, Pedro L Rosalen, José A Lemos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0124969