Efficient Sonogashira Coupling Reaction Catalyzed by Copper (I) Iodide in the Presence of KF/Al2O3
We have developed a convenient and efficient method for coupling of aryl iodides and bromides with terminal alkynes. The protocol uses CuI as catalyst, 1, 10-phenanthroline as ligand, KF/Al2O3 as base and toluene as solvent. The method is suitable for the synthesis of functionalized aryl-alkynes.
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Semnan University
2009-05-01
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| Series: | شیمی کاربردی روز |
| Subjects: | |
| Online Access: | https://chemistry.semnan.ac.ir/article_544_9d7a022e5c32e19004ec207e0d2a4957.pdf |