Brain insulin sensitivity is linked to adiposity and body fat distribution

Brain insulin action regulates eating behavior and whole-body energy fluxes, however the impact of brain insulin resistance on long-term weight and body fat composition is unknown. Here, the authors show that high brain insulin sensitivity is linked to weight loss during lifestyle intervention and a...

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Bibliographic Details
Main Authors: Stephanie Kullmann, Vera Valenta, Robert Wagner, Otto Tschritter, Jürgen Machann, Hans-Ulrich Häring, Hubert Preissl, Andreas Fritsche, Martin Heni
Format: Article
Language:English
Published: Nature Portfolio 2020-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-15686-y