The extract of roots of Sophora flavescens enhances the recovery of motor function by axonal growth in mice with a spinal cord injury

The extract of roots of Sophora flavescens enhances the recovery of motor function by axonal growth in mice with a spinal cord injury

Although axonal extension to reconstruct spinal tracts should be effective for restoring function after spinal cord injury (SCI), chondroitin sulfate proteoglycan (CSPG) levels increase at spinal cord lesion sites and inhibit axonal regrowth. In this study, we found that the water extract of roots o...

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Bibliographic Details
Main Authors: Norio eTanabe, Tomoharu eKuboyama, Kohei eKazuma, Katsuhiro eKonno, Chihiro eTohda
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-01-01
Series:Frontiers in Pharmacology
Subjects:
spinal cord injury
axonal growth
Chondroitin sulfate proteoglycan
matrine
Oxymatrine
Sophora flavescens
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00326/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00326/full

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