Exploration of treatment‐free remission in CML, based on molecular monitoring

Exploration of treatment‐free remission in CML, based on molecular monitoring

Abstract Background Typical chronic myelogenous leukemia (CML) is a myeloproliferative neoplasm caused by t(9; 22)(q34; q11) translocation. This chromosomal translocation forms the BCR::ABL1 fusion gene. The tyrosine kinase encoded by the BCR::ABL1 is considered to be the main pathogenic diver. BCR:...

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Bibliographic Details
Main Authors: Zhao Zhang, Xianghui Zhou, Xin Zhou, Zhipeng Cheng, Yu Hu
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Cancer Medicine
Subjects:
BCR::ABL1
chronic myelogenous leukemia
deep molecular response
molecular monitoring
treatment‐free remission
tyrosine kinase inhibitor discontinuation
Online Access:https://doi.org/10.1002/cam4.6849

Internet

https://doi.org/10.1002/cam4.6849

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